姓名 | 吴聪 | |
工作单位 | 海军军医大学第一附属医院 | |
职称 | 副主任技师 | |
导师资格 | 硕士研究生导师 | |
招生学科 | 生物医学工程学科 | |
联系方式 | 13402164537 | |
一、个人简介 吴聪,免疫学博士,临床检验诊断学博士后,海军军医大学第一附属医院(上海长海医院)硕士生导师。现任长海医院临床样本库执行负责人,主要研究方向为肿瘤分子及免疫诊断,样本库信息化建设及相关大数据研究。在Science、advanced science,Journal of Immunology、Cellular and Molecular Immunology、Nanomedicine等期刊发表多篇SCI论文,副主编诊断学教材一部,主持国家自然科学基金、国防科技项目、中国博士后科学基金等多项国家和军队级科研项目,入选海军军医大学“远航”人才计划。 | ||
二、主要学习与工作经历 2001/09-2006/06,泰山医学院,临床医学系,学士 2006/09-2009/06,第二军医大学,医学免疫学国家重点实验室,硕士 2009/09-2013/06,浙江大学,医学院免疫学系,博士 2013/07-2016/07,第二军医大学,长海医院,主管技师 2016/12-至今,海军军医大学第一附属医院,副主任技师 | ||
三、主要研究方向 肿瘤进展及转移相关的分子机制研究;肿瘤分子及免疫诊断;样本库信息化建设及大数据研究。
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四、主要科研工作与成绩 1、国防科技项目管理中心,基础加强计划技术领域基金项目,2019-JCJQ-JJ-066,基于氧化石墨烯的抗蓖麻毒素核酸适配体纳米阵列,2020-01至2021-12,50万元,在研,主持 2、海军军医大学,“远航”军事医学人才类项目,2019-YH-09,岛礁疾病谱样本保藏策略及信息化建设研究,2020-01至2021-12,20万元,在研,主持 3、国家自然科学基金委员会,重点项目,81730076,hsa_circ_RPPH1 / hsa_circ_00 03596调控循环肿瘤干细胞间充质-上皮转化促进肝癌转移的机制研究,2018-01至2022-12 ,290万元,在研,参与 4、中国博士后科学基金面上资助,LOC101929219在卵巢癌转移中的作用机制研究,2017-06至2019-06,结题,主持 5、国家自然科学基金委员会,青年项目,31400778,磷酸酶PTEN在巨噬细胞介导的抗隐球菌固有免疫反应中的作用机制研究,2015-01至2017-12,25万元,结题,主持 主持或参加科研项目: 2015-01至2017-12,25万元,结题,主持 发表论著: 1、Liang Chen#, Ruijiao Kong#, Cong Wu, Shuo Wang, Zixin Liu, Shupeng Liu, Shuiping Li, Tian Chen, Chuanbin Mao*, and Shanrong Liu*. Circ-MALAT1 Functions as Both an mRNA Translation Brake and a microRNA Sponge to Promote Self-Renewal of Hepatocellular Cancer Stem Cells. Adv Sci (Weinh) 2020, 7(4): 1900949. 2、Huimin Ma# , Meng Yu# , Cong Wu, Houbao Huang, Yawei Li, Peng Zhang, Jianjun Huang, Long Cheng, Gang Feng* , Guorong Li, Overexpression of Spondin-2 Is Associated with Recurrence-Free Survival in Patients with Localized Clear Cell Renal Cell Carcinoma, Disease Markers, 2020; 2020(88):5074239. 3、Cong Wu#, Wei Wan#, Ji Zhu, Hai Jin, Tiejun Zhao*, Huafei Li*, Induction of potent apoptosis by an anti-CD20 aptamer via the crosslink of membrane CD20 on non-Hodgkin’s lymphoma cells, RSC Advances, 2017, 7:5158-5166. 4、Hua-Fei Li#,*, Cong Wu#, Ting Chen#, Ge Zhang, He Zhao, Chang-Hong Ke, Zheng Xu*, Construction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity, International Journal of Nanomedicine, 2015, 10:4783-96. 5、Huafei Li#, Cong Wu#, Mao Xia#, He Zhao, Mengxin Zhao, Jin Hou, Rong Li, Lixin Wei*, Li Zhang*, Targeted and controlled drug delivery using a temperature and ultra-violet responsive liposome with excellent breast cancer suppressing ability, RSC Advances, 2015, 5(35):27630-39. 6、Huafei Li#, Kun Guo#, Cong Wu#, Ling Shu, Shiwei Guo, Jing Hou, Naping Zhao, Lixin Wei, Xiaobo Man, Li Zhang*, Controlled and Targeted Drug Delivery by a UV-responsive Liposome for Overcoming Chemo-resistance in Non- Hodgkin Lymphoma, Chem Biol Drug Des, 2015, 86(4):783-94. 7、Cong Wu#, Huafei Li#,*, He Zhao#, Weiwei Zhang, Yan Chen, Zhanyi Yue, Qiong Lu, Yuxiang Wan, Xiaoxu Tian, Anmei Deng*. Potentiating antilymphoma efficacy of chemotherapy using a liposome for integration of CD20 targeting, ultra-violet irradiation polymerizing, and controlled drug delivery, Nanoscale Res Lett, 2014, 9(1): 447. 8、Cong Wu#, Huafei Li#,*, He Zhao#, Weiwei Zhang, Yan Chen, Zhanyi Yue, Qiong Lu, Yuxiang Wan, Xiaoxu Tian, Anmei Deng*. Potentiating antilymphoma efficacy of chemotherapy using a liposome for integration of CD20 targeting, ultra-violet irradiation polymerizing, and controlled drug delivery, Nanoscale Res Lett, 2014, 9(1): 447. 9、Cong Wu#, Yi Zhang#, Yingming Jiang, Quanxing Wang, Yao Long, Chunmei Wang, Xuetao Cao*, Guoyou Chen*, Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells, Cell Mol Immunol, 2013, 10(5): 393-402. 10、Pin Wang, Yiquan Xue, Yanmei Han, Li Lin, Cong Wu, Sheng Xu, Zhengping Jiang, Junfang Xu, Qiuyan Liu, Xuetao Cao*, The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation, Science, 2014, 344(6181):310-313. 11、Pin Wang#, Yan Gu#, Qian Zhang#, Yanmei Han, Jin Hou, Li Lin, Cong Wu, Yan Bao, Xiaoping Su, Minghong Jiang, Qingqing Wang, Nan Li, Xuetao Cao*, Identification of resting and type I IFN-activated human NK cell miRNomes reveals microRNA-378 and microRNA-30e as negative regulators of NK cell cytotoxicity, J Immunol, 2012, 189(1):211-221. 12、李林林, 吴聪*. 长链非编码RNA 在自身免疫性疾病中的研究进展[J]. 基础医学与临床, 2019,39(4):573-576. 13、吴聪, 方超萍, 俞靖龙, 刘善荣*. 精准医学给予检验医学的机遇与挑战[J]. 中华检验医学杂志, 2017, 40(01):14-16.
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五、主要社会学术团体兼职 无
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