姓名 | 王晓强 |
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职称 | 副主任医师 | |
导师资格 | 硕导 | |
学科专业 | 神经外科 | |
联系方式 | 电话：13817976179 E-mail：wangxiaoqiang419@163.com | |
一、个人简介 国家级神经外科专科医师培训基地考官，中国医师协会专科医师结业考考官。副主任医师，博士后，硕士生导师，哈佛大学及加州大学旧金山分校高级访问学者，师从美国小儿神经外科协会主席MichaelScott教授，系统学习儿童神经系统肿瘤及先天性、遗传性神经系统疾病的综合诊断与治疗。系国家教育部博士论文评审专家，科技部国家自然科学基金评审专家。近年主持国家自然科学基金等项目十余项。副主编专著3部，参编专著10部，以第一作者/通讯作者在国际权威期刊发表论文五十余篇，担任Neurosurgery、JNS、BMCNeurology、ChildNervous System、《重庆医科大学学报》等十余家SCI杂志及国内核心期刊编委或特约审稿人。 | ||
二、主要学习与工作经历 1. 学习经历： (1) 2018-12至2019-12，哈佛大学，BostonChildren’s Hospital，访问学者 (2) 2006-09至2009-08，上海交通大学医学院附属瑞金医院神经外科博士 (3) 2004-09至2006-08，上海交通大学医学院附属瑞金医院神经外科，硕士 (4) 1991-09至1996-08，华北煤炭医学院临床医学系，学士 2. 工作经历： (1) 2013-12至现在，上海交通大学医学院附属新华医院小儿神经外科，副主任医师 (2) 2012-01至2013-11，上海交通大学医学院附属新华医院神经外科，主治医师 (3) 2009-09至2011-12，复旦大学华山医院博士后流动站，博士后 (4) 2001-09至2004-08，河北省唐山地区人民医院神经外科，主治医师 (5)1996-09至2001-08，河北省唐山地区人民医院神经外科，住院医师 | ||
三、主要科研工作与成绩 （一）科研项目： 1.国家自然科学基金面上项目，No.81171235/H0914，神经外科功能区手术临床和基础研究（主持） 2.上海市自然科学基金面上项目，No.ZR1426800，Lamininγ1在恶性脑膜瘤侵袭中的作用及其分子机制研究（主持） 3.上海市自然科学基金面上项目，No.ZR186822，弥散张量成像联合磁敏感成像在脑损伤预后评判中作用研究（主持） 4.上海交通大学新华医院基金，No.2012080801，恶性脑膜瘤临床生物学行为评估（主持） 5.上海交通大学新华医院临床研究项目，No.15LC19，弥散张量成像对弥漫性轴索损伤患者预后评判研究（主持） 5.上海交通大学医工合作基金，No.YG2014MS68，血流动力学监测在预测颅内动脉瘤血管内治疗后远期复发研究（主持） 6.中国博士后基金，No.20100480568，针刺在幕下开颅手术后镇吐作用研究（主持） 7.上海交通大学医学院基金，中枢神经系统肿瘤临床整合式课程建设（主持） 8.上海交通大学医学院基金，多模态教学模式在神经外科临床带教中的应用研究（主持） 9.上海市境外人才计划，儿童髓母细胞瘤中美比较及预后生存分析(主持) （二）代表性论文： 1. Yang YM, Han Y,Sun QY, Cheng Y, Cui DX, Wang XQ* （通讯作者）.Au-siRNA@ ApatmerNanocages as a High-Efficiency Drug and GeneDelivery System for Targeted Cancer Therapy. J Nanobiotechnology.2021, 19 (1), 54. (IF：10.435). 4. Zhang WB, MinLZ, Tao BB, Sun QY, Li ST, Wang XQ*（通讯作者）.PrognosisComparison of Different Branches of Trigeminal Neuralgia.WorldNeurosurg. 2019 Jun 25. (SCI). 5. Min LZ, Liu MX,Zhang WB, Tao BB, Sun QF, Li ST, Wang XQ*（通讯作者）.Outcomesand Safety of Overlapping Surgery in Patients UndergoingMicrovascular Decompression for Hemifacial Spasm and TrigeminalNeuralgia. World Neurosurg. 2019 Oct;130:e1084-e1090.(SCI). 6. Min L, Zeng X, LiB, Tao B, Shi J, Zhang W, Sun Q, Jing C, Wang XQ*（通讯作者）.Overexpressionof immunoproteasome low-molecular-mass polypeptide 7 andinhibiting role of next-generation proteasome inhibitor ONX 0912on cell growth in glioma. Neuro report. 2019 Sep9. (SCI).7. Sun FB, Xia YH, Shi JH, Min LZ, Li B, WangXQ*（通讯作者）.Intracranialembryonal carcinoma: a clinicopathologic study of ten cases andreview of the literature. Int J Clin Exp Pathol2017;10(4):4461-4469. (SCI). 8. Wang XQ（第一作者）,Che Z, Dong W, Guo X, Wang Z, Chen P, Hou D, Zhang Q, Zhang W, PanY, Yang D, Liu H. Targeting high Aurora kinases expression as aninnovative therapy for hepatocellular carcinoma. Oncotarget. 201725;8(17):27953-27965. doi: 10.18632/oncotarget.15853. (SCI). 9. Wang XQ（第一作者）,Bai HM, Li ST, Sun H, Min LZ, Tao BB, Zhong J, Li B. Knockdown ofHDAC1 expression suppresses invasion and induces apoptosis inglioma cells. Oncotarget. 2017 18;8(29):48027-48040. doi:10.18632/oncotarget.18227. (SCI). 10. WangXQ（第一作者），TaoBB, Li ST*，WangXH，ZhangWB, Wan L，HuaXM and Li B*. Overexpression of TREM2 enhances glioma cellproliferation and invasion: a therapeutic target in human glioma.Oncotarget. 7(3):2354-6,2016. (SCI). 11. Li B , Huang MZ,Wang XQ*（通讯作者）,Tao BB, Zhong J, Wang XH, Zhang WC, and Li ST*. TMEM140 isassociated with the prognosis of glioma by promoting cellviability and invasion. Journal of Hematology & Oncology.8:89. doi: 10.1186/s13045-015-0187-4,2015. (SCI). 12. Li ST, Pan J,Hua XM, Liu H, Shen S, Liu JF, Li B, Tao BB, Ge XL, Wang XH, ShiJH, Wang XQ*（通讯作者）.Endothelial nitric oxide synthase protects neurons againstischemic injury through regulation of brain-derived neurotrophicfactor expression. CNS Neurosci Ther. 20(2):154-64, 2014. (SCI). 13. Wang XQ（第一作者）,Huang MZ, Zhang H, Sun FB, Tao BB, Feng BH, Liao CL, Kochanski R,Hua XM, Li ST. Clear cell meningioma: clinical features, CT, andMR imaging findings in 23 patients. J Comput Assist Tomogr.38(2):200-8, 2014. (SCI). 14. Wang XQ（第一作者）,Zhou Q, Li ST, Liao CL, Zhang H, Zhang BY. Solitary fibrous tumorsof the central nervous system: clinical features and imagingfindings in 22 patients. J Comput Assist Tomogr.37(5):658-65,2013. (SCI). 15. Ke HL, Ke RH, LiB, Wang XH, Wang YN, Wang XQ*（通讯作者）.Association between laminin gamma1 expression and meningiomagrade, recurrence, and progression-free survival. Acta Neurochir(Wien). 155(1):165-71, 2013. (SCI). 16. Ke HL, Ke RH, LiST, Li B, Lu HT, Wang XQ*（通讯作者）.Expression of RACGAP1 in high grade meningiomas: a potential rolein cancer progression. Journal of Neuro-oncology. 113(2):327-32 ,2013. (SCI). 17. Wang XQ（第一作者）,Chen H, Li ST, Hu J, Mei GH, Zhao L, Jiang CC*. Intracranialpapillary meningioma: a clinicopathologic study of 30 cases at asingle institution. Neurosurgery. 73(5):777-90, 2013. (SCI). 18. Li ST, Tao BB,Gao Z, Li B, Wu Y, Feng BH, Wang XQ*（通讯作者）.Clinical features and treatment of cavernous angiomas in thefourth ventricle: a series of six patients and review of theliterature. Journal of Neurological Sciences (Turkish), 30(2):356-368, 2013. (SCI). 19. Wang XQ（第一作者）,Mei GH, Zhao L, Li ST, Gong Y, Zhong J, Chen H*. Clinical featuresand treatment of intracranial chordoid meningioma: a report of 30cases. Histopathology. 62(7):1002-17, 2013. (SCI). 20. Zhu H, Qiu LH,Dou YF, Wu JS, Zhong P, Jiang CC, Wang XQ*（通讯作者）.Imaging characteristics of Rosai-Dorfman disease in the centralnervous system. Eur J Radiol. 81(6):1265-72, 2012. (SCI). 21. Chen H, Xiao CW,Wang T, Wu JS, Jiang CC, Qian J, Wang XQ*（通讯作者）.Orbital solitary fibrous tumor: a clinicopathologic study of tencases with long-term follow-up. Acta Neurochir (Wien).154(2):249-55, 2012. (SCI). 22. Zhang BY, Yin B,Li YX, Wu JS, Chen H, Wang XQ*（通讯作者）.Neuroradiological findings and clinical features offourth-ventricular meningioma: a study of 10 cases. Clin Radiol.67(5):455-60, 2012. (SCI). 23. Wang XQ（第一作者）,Jiang CC, Zhao L, Gong Y, Hu J, Chen H*. Clinical features andtreatment of World Health Organization grade II and IIImeningiomas in childhood: report of 23cases. J Neurosurg Pediatr.10(5):423-33, 2012. (SCI). 24. Wang XQ（第一作者）, Zeng XW, Zhang BY, Dou YF, Wu JS, Jiang CC, Zhong P*. Spinalmeningioma in childhood: clinical features and treatment. ChildsNerv Syst. 28(1):129-36, 2012. (SCI). 25. Chen H, Zeng XW,Wu JS, Dou YF, Wang Y, Zhong P, Wang XQ*（通讯作者）.Solitary fibrous tumor of the central nervous system: aclinicopathologic study of 24 cases. Acta Neurochir (Wien).154(2):237-48, 2012. (SCI). 26. Li J, Li ST, ZhuMJ, Li YM, Wang X, Li YJ, Wang XQ*（通讯作者）.Clinical features and treatment of spinal myxopapillaryependymoma: a series of 15 cases Journal of Neurological Sciences(Turkish). 29(4):794-803, 2012. (SCI). 27. Li ST, Hu WZ,Kochanski R, Zhang WC, Tao BB, Lu HT, Li B, Wang XQ*（通讯作者）.Cavernous angiomas of the third ventricle: a series of eightpatients and review of the literature. Journal of NeurologicalSciences (Turkish). 29(4):863-76, 2012. (SCI). 28. Xu M, Zhou SJ,Jiang CC, Wu Y, Shi WL, Gu HH, Wang XQ*（通讯作者）.The effects of P6 electrical acustimulation on postoperativenausea and vomiting in patients after infratentorial craniotomy. JNeurosurg Anesthesiol. 24(4):312-6, 2012. (SCI). 29. Zeng XW, Li B,Wang XQ*（通讯作者）.Solitary fibrous tumor of the lumbar spine: case report and reviewof the literature Journal of Neurological Sciences (Turkish).29(3):623-30, 2012. (SCI). 30. Zeng XW, Li MW,Pan J, Ji TL, Yang B, Zhang B, Wang XQ*（通讯作者）.Activation of c-Jun N-terminal kinase 1/2 regulated by nitricoxide is associated with neuronal survival in hippocampal neuronsin a rat model of ischemia. Chin Med J (Engl). 124(20):3367-72,2011. (SCI). 31. Chen H, Li XM,Chen YC, Wu JS, Dou YF, Wang Y, Wang XQ*（通讯作者）.Intracranial clear cell meningioma: a clinicopathologic study of15 cases. Acta Neurochir (Wien). 153(9):1769-80, 2011. (SCI). 32. Zhang BY, ChenH, Geng DY, Yin B, Li YX, Zhong P, Wang XQ*（通讯作者）.Computed tomography and magnetic resonance features ofgliosarcoma: a study of 54 cases. J Comput Assist Tomogr.35(6):667-73, 2011. (SCI). 33. Hu J, Hu JQ,Jiang CC, Wang XQ*（通讯作者）.Ruptured aneurysm at the origin of the median artery of the corpuscallosum: case report. Journal of Neurological Sciences (Turkish).28(4):632-36, 2011. (SCI). 34. Wang XQ（第一作者）,Yu JL, Du ZY, Xu R, Jiang CC, Gao X*. Electroacupoint stimulationfor postoperative nausea and vomiting in patients undergoingsupratentorial craniotomy. J Neurosurg Anesthesiol. 22(2):128-31,2010. (SCI). 35. Zhang WB, ZengYY, Wang F, Cheng L, Tang WJ, Wang XQ*（通讯作者）.Prognosticnomogram for microvascular decompression-treated trigeminalneuralgia [J]. Neurosurgical re view, 2020. (SCI). 36. Yang YM, Sun QY,Cui FF, Wang XQ*（通讯作者）.Au-siRNA@ Apatmer Nanocages as a High-Efficiency Drug and GeneDelivery System for Targeted Lung Cancer Therapy [J]. SignalTransduction and Targeted Therapy, 2020. (SCI) 37. Min LZ, ZhangWB, Wang XQ*（通讯作者）.Hypertension and Diabetes Are Associated With ClinicalCharacteristics in Patients Undergoing Microvascular Decompressionfor Hemifacial Spasm [J]. The Journal of craniofacial surgery,2020, 31(2): 468-71.(SCI). 38. Zhang WB, SunQY, Min LZ, Tao BB, Wang XQ*（通讯作者）.The RiskFactors for Facial Numbness After Microvascular Decompression inPatients With Trigeminal Neuralgia. J Craniofac Surg.2019,30(8):e710-e713. (SCI). 39. Zhang WB, MinLZ, Zhong WX, Tao BB, Li B, Sun QY, Wang XQ*（通讯作者）.Surgicaleffect and electrophysiological study of patients with hemifacialspasm treated with botulinum toxin or acupuncture beforemicrovascular decompression. Clin Neurol Neurosurg. 2019 Sep.(SCI). 40. Song JJ, LiL, Min LZ, Chen D*, Wang XQ*（通讯作者）.Afunctional variant in the 3′UTR of LAMB3 is associated withincreased glioma risk. Cancer Communications. 2020. | ||
四、主要社会学术团体兼职 1. 中国神经微侵袭治疗委员会委员 2. 中国医师协会创伤分会委员 3. 上海市医学会神经外科分会青年委员 4. 上海市中西医结合神经外科常委 5. 上海市康复医学会重症康复委员 6. 上海大学转化医学研究院外聘教授 7.内蒙古医科大学外聘研究生导师 | ||
五、主要研究方向 2.智能影像技术及神经系统疾病辅助诊疗。 | ||
